New Research Sheds Light on the Inflammation–Mood Connection 

As we age, our bodies change — and so does our mental health. Depression in older adults is a growing concern, often overlooked or misattributed to aging. But what if part of the solution lies in reducing inflammation?

A recent systematic review and meta-analysis, published on ResearchGate, offers compelling evidence that targeting inflammation could help ease or even prevent depression in people over 60.

What Did the Study Explore?

Researchers analyzed 27 randomized controlled trials involving over 6,600 participants. They evaluated the effects of various anti-inflammatory treatments, including:

• Omega-3 fatty acids
• NSAIDs (like aspirin)
• Statins
• Probiotics

• Lifestyle interventions (like diet and exercise)

The Main Findings

• Anti-inflammatory strategies showed a statistically significant reduction in depressive symptoms.

• Omega-3 supplements in particular were associated with the most consistent benefits and the fewest side effects.

• However, not all interventions were equally effective — and results varied based on the participants’ health status and treatment type.

Why Is This Important?

This research reinforces the idea that mental health and inflammation are closely linked. It opens the door to integrative, low-risk approaches that could support emotional well-being — particularly for those who are hesitant about antidepressants.

Try It Yourself – Natural Ways to Support Mental Health Through Inflammation Control

• Cook with turmeric, ginger, and leafy greens
• Enjoy omega-3-rich foods like flax, chia seeds, or wild salmon
• Add probiotic-rich foods like miso, kefir, or fermented veggies
• Stay active with gentle movement – walking, yoga, or swimming
• Support your gut with fiber and hydration

Reference:
Ng, T. P. et al. Anti-inflammatory interventions for the treatment and prevention of depression among older adults: a systematic review and meta-analysis. ResearchGate, 2024. View the study